产品信息 - albendazole tablet ,suspension ,injection->veterinary medicine

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Jian HEK animal health co.,ltd

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albendazole tablet ,suspension ,injection

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生化科技->生化->獸藥

albendazole tablet ,suspension ,injection

产品规格

Country	CN
Payment Term	tt

产品描述

Albendazole Bolus/tablet,Suspention
Specifications
veterinary albendazole bolus
300mg.600mg.2500mg
veterinary Albendazole bolus
Albendazole
Molecular formula: C12H15N3O2S
CAS No: 54965-21-8
Molecular Weight: 265.33
Synonyms: Methyl 5-propylthio-2-benzimidazolecarbamate
Formulations: Not Available
Indication
For the treatment of parenchymal neurocysticercosis due to active lesions caused by larval forms of the pork tapeworm, Taenia solium and for the treatment of cystic hydatid disease of the liver, lung, and peritoneum, caused by the larval form of the dog tapeworm, Echinococcus granulosus.
Pharmacology
Albendazole is a broad-spectrum anthelmintic. The principal mode of action for albendazole is by its inhibitory effect on tubulin polymerization which results in the loss of cytoplasmic microtubules.
Mechanism of Action Albendazole causes degenerative alterations in the tegument and intestinal cells of the worm by binding to the colchicine-sensitive site of tubulin, thus inhibiting its polymerization or assembly into microtubules. The loss of the cytoplasmic microtubules leads to impaired uptake of glucose by the larval and adult stages of the susceptible parasites, and depletes their glycogen stores. Degenerative changes in the endoplasmic reticulum, the mitochondria of the germinal layer, and the subsequent release of lysosomes result in decreased production of adenosine triphosphate (ATP), which is the energy required for the survival of the helminth. Due to diminished energy production, the parasite is immobilized and eventually dies.

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