产品信息 - Strontium ranelate 99% CAS NO 135459-87-9->pharmaceutical

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Strontium ranelate 99% CAS NO 135459-87-9

产品分类 :

化學->藥品->醫藥

Strontium ranelate 99% CAS NO 135459-87-9

产品规格

Model No: cy13459-87-9

Country	CN
Brand	chenyi
Packing	25kg
Minimum Order	25
Payment Term	L/C,T/T

产品描述

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<span style="font-size:12px;"><span style="font-size:12px;">Strontium ranelate 99% CAS NO 135459-87-9</span><br />
Strontium ranelate, a strontium(II) salt of ranelic acid, is a medication for osteoporosis marketed as Protelos or Protos by Servier. Studies indicate it can also slow the course of osteoarthritis of the knee. The drug is unusual in that it both increases deposition of new bone by osteoblasts and reduces the resorption of bone by osteoclasts. It is therefore promoted as a "dual action bone agent" (DABA).</span>
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<span style="font-size:12px;">On 13 May 2013, Servier released a Direct Healthcare Professional Communication which stated that new restrictions for the use of strontium ranelate are now in place, as randomised trials have shown an increased risk of myocardial infarction. Servier states that the use is now restricted to treatment of severe osteoporosis in postmenopausal women at high risk for fracture. The European Pharmacovigilance Risk Assessment Committee (PRAC) recommends restriction in the use of strontium ranelate, based on a routine benefit-risk assessment of the medicine, which included data showing an increased risk of heart problems, including heart attacks. On 21 February 2014 the European Medicine Agency recommended that strontium ranelate remain available with restrictions relative to patients with existing heart disease.</span>
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<span style="font-size:12px;">Strontium ranelate</span>
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<span style="font-size:12px;">Chinese Name: strontium ranelate</span>
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<span style="font-size:12px;">English Name: 2,2'-((5-Carboxy-4-(carboxymethyl) -3-cyanothiophen-2-yl) azanediyl) diacetic acid, distrontium salt</span>
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<span style="font-size:12px;">English alias: Ranelic Acid Strontium Salt; Strontium Ranelate; Strontium ranelate; CAS number: 135459-87-9</span>
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<span style="font-size:12px;">Molecular formula: C12H6N2O8SSr2</span>
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<span style="font-size:12px;">Molecular weight: 513.49000</span>
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<span style="font-size:12px;">Precise quality: 513.79600</span>
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<span style="font-size:12px;">PSA:160.47000</span>
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<span style="font-size:12px;">Physicochemical properties</span>
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<span style="font-size:12px;">Appearance and properties: crystalline solids</span>
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<span style="font-size:12px;">Boiling point: 778.8 C at 760 mmHg</span>
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<span style="font-size:12px;">Flash point: 424.8 x C</span>
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<span style="font-size:12px;">security information</span>
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<span style="font-size:12px;">Symbol:</span>
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<span style="font-size:12px;">GHS07</span>
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<span style="font-size:12px;">Signal word: warning</span>
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<span style="font-size:12px;">Hazard statement: H302 + H312 + H332</span>
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<span style="font-size:12px;">Cautionary statement: P280</span>
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<span style="font-size:12px;">Customs Code: 2942000000</span>
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<span style="font-size:12px;">purpose</span>
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<span style="font-size:12px;">Anti-osteoporosis drugs are mainly used to treat and prevent osteoporosis in postmenopausal women, significantly reducing the risk of vertebral and hip fractures.</span>
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<br />chenyichem.com

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